Best for · stress
Stress & Anxiety
Anxiolytic support without sedation centers on alpha-wave promotion (L-Theanine), GABA modulation (magnesium, ashwagandha), and HPA-axis blunting (adaptogens). Skip phenibut for daily use — its dependence profile is severe.
Ranked substances
| # | Substance | Category | Typical dose | Evidence | Safety | In stacks |
|---|---|---|---|---|---|---|
| 1 | Ashwagandha | adaptogen | 300–600mg | EVIDENCEA | ●●●●● | 3 |
| 2 | L-Theanine | amino-acid | 100–400mg | EVIDENCEA | ●●●●● | 2 |
| 3 | Rhodiola Rosea | adaptogen | 200–400mg | EVIDENCEA | ●●●●● | 2 |
| 4 | Magnesium Glycinate | neuroprotective | 200–400mg | EVIDENCEB | ●●●●● | 2 |
| 5 | Phosphatidylserine (PS) | cholinergic | 100–300mg | EVIDENCEB | ●●●●● | 1 |
Curated stacks for stress
beginner
Anxiety Reduction Stack
Daily anxiolytic support without sedation. Adaptogenic + GABA-supporting natural compounds.
$1.10/dayOpen
beginnerSocial Confidence Stack
Pre-social acute anxiolytic without sedation. Not for daily use of phenibut.
$1.40/dayOpen
intermediateStress Resilience Stack
Multi-adaptogen protocol for chronic high-stress periods. Modulates HPA axis from multiple angles.
$2.40/dayOpen
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