Comparison
Magnesium L-Threonate vs Pomegranate Extract
Magnesium L-Threonate
MIT-developed magnesium that crosses the blood-brain barrier. Shown to enhance synaptic density and reduce 'brain age'.
Pomegranate Extract
Standardised extract rich in punicalagins. Cardiovascular and cognitive benefits; metabolised to urolithins by gut bacteria.
| Field | Magnesium L-Threonate | Pomegranate Extract |
|---|---|---|
| Category | neuroprotective | neuroprotective |
| Dose range | 1000–2000mg | 250–1000mg |
| Half-life | 6h | — |
| Onset | — | — |
| Evidence | EVIDENCEB | EVIDENCEB |
| Safety | ●●●●● | ●●●●● |
| Legal (US) | USOTC | USOTC |
| PubMed refs | 90 | 1200 |
The comparison in plain English
Auto-generated from dataMagnesium L-Threonate and Pomegranate Extract are both in the neuroprotective category respectively. Magnesium L-Threonate MIT-developed magnesium that crosses the blood-brain barrier. Pomegranate Extract Standardised extract rich in punicalagins.
Bottom line
Magnesium L-Threonate (evidence B, safety 5/5) matches the evidence base of Pomegranate Extract (evidence B, safety 5/5). Magnesium L-Threonate has the slightly cleaner safety profile. For users new to either, the higher-evidence option is the safer first try.
Choose Magnesium L-Threonate if
Magnesium L-Threonate is the better fit when your goal aligns with its mechanism (L-threonate is a sugar-acid carrier that uniquely enables magnesium to cross the blood-brain barrier in meaningful quantities — most oral magnesium forms (oxide, citrate, glycinate) raise serum magnesium but not central magnesium) and the dose range (1000–2000mg) suits your protocol. Half-life is 6h.
Choose Pomegranate Extract if
Pomegranate Extract is the better fit when your goal aligns with its mechanism (Punicalagins and other ellagitannins are metabolised by gut bacteria to urolithin A and related compounds) and the dose range (250–1000mg) suits your protocol. Half-life is —h.