vitaminEVIDENCEAUSOTC

Selenium

Essential trace mineral; cofactor for glutathione peroxidase and thyroid hormone activation. Brazil nuts are the densest food source.

Dose range0.05–0.2mg

Half-life—h

Onset—min

Safety4/5high evidence base

Mechanism of action

Component of selenoproteins (glutathione peroxidases, deiodinases). Critical for antioxidant defense and T4→T3 conversion.

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