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neuroprotectiveEVIDENCECUSOTC

PQQ

aka Pyrroloquinoline quinone

Pyrroloquinoline quinone — cofactor in mitochondrial biogenesis. Found in fermented foods and breast milk.

Dose range10–40mg
Half-lifeh
Onsetmin
Safety5/5medium evidence base

Mechanism of action

Stimulates mitochondrial biogenesis via PGC-1α. Antioxidant. May potentiate CoQ10.

Benefits

  • Cognitive function

    EVIDENCEC

    Itoh 2016 small RCT.

  • Mitochondrial biogenesis

    EVIDENCEB

    Animal + mechanism.

Side effects

  • Mild headacheraremild

Where to buy

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