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neuroprotectiveEVIDENCEAUSOTC

Nicotinamide Riboside (NR)

aka NR · Niagen

NAD+ precursor — the most-studied form for direct NAD+ elevation in humans. Branded as Niagen.

Dose range250–1000mg
Half-lifeh
Onsetmin
Safety5/5high evidence base

Mechanism of action

Precursor in the NAD+ salvage pathway. Multiple RCTs show ~40-90% NAD+ increases.

Benefits

  • NAD+ elevation

    EVIDENCEA

    Trammell 2016, Dollerup 2018.

  • Cardiovascular markers

    EVIDENCEB

    Martens 2018.

Side effects

  • Mild flushing (high dose)raremild

Where to buy

Affiliate links
VendorProductSizePricePer unit
Nootropics DepotFeatured 4.8Nicotinamide Riboside Capsules, 30ct (250mg)30 × 250mg$29.99$1.00Buy
Double Wood Supplements 4.4Nicotinamide Riboside, 60ct (300mg)60 × 300mg$49.99$0.83Buy