cholinergicEVIDENCEAUSRx
Galantamine
aka Reminyl · Razadyne
Prescription cognitive enhancer derived from snowdrop. Selective AChE inhibitor + allosteric nicotinic potentiator.
Dose range4–12mg
Half-life7h
Onset60min
Safety3/5high evidence base
Mechanism of action
Reversibly inhibits acetylcholinesterase. Allosterically potentiates nicotinic ACh receptors. Crosses BBB.
Benefits
Mild-to-moderate Alzheimer's
EVIDENCEAMultiple RCTs.
Lucid dreaming (anecdotal)
EVIDENCECPopular for REM-stage dream induction.
Side effects
- Nausea / vomitingcommonmoderate
- Bradycardiauncommonmoderate
Where to buy
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