neuroprotectiveEVIDENCEBUSOTC
Fisetin
Flavonoid found in strawberries. Senolytic — selectively clears senescent cells. Promising longevity intervention.
Dose range100–500mg
Half-life—h
Onset—min
Safety4/5medium evidence base
Mechanism of action
Senolytic activity (clears senescent cells). Inhibits PI3K/AKT/mTOR. Antioxidant. Neuroprotective.
Benefits
Senolytic activity in vivo
EVIDENCEBYousefzadeh 2018 EBioMedicine.
Cognitive aging (animal models)
EVIDENCECCurrais 2018.
Side effects
- Mild blood-thinninguncommonmild
Where to buy
Affiliate links| Vendor | Product | Size | Price | Per unit | |
|---|---|---|---|---|---|
| Nootropics DepotFeatured 4.8 | Fisetin Capsules, 30ct (100mg) | 30 × 100mg | $19.99 | $0.67 | Buy |
| Double Wood Supplements 4.4 | Fisetin, 30ct (100mg) | 30 × 100mg | $24.99 | $0.83 | Buy |