vitaminEVIDENCEAUSOTC
B-Complex
B vitamins (B1, B2, B3, B5, B6, B7, B9, B12) are cofactors in nearly all neurotransmitter synthesis. Deficiency causes cognitive and mood symptoms.
Dose range50–150mg
Half-life—h
Onset—min
Safety5/5high evidence base
Mechanism of action
Each B vitamin serves as a cofactor in different methylation, energy, and neurotransmitter pathways.
Benefits
Methylation / homocysteine
EVIDENCEAUniversally accepted.
Mood support (when deficient)
EVIDENCEBMultiple RCTs in deficient populations.
Side effects
- Bright yellow urine (B2 excretion)commonmild
- Niacin flush (B3)commonmild
Where to buy
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