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stimulantEVIDENCEAUSSchedule IV

Armodafinil

aka Nuvigil · Waklert · Artvigil

The R-enantiomer of modafinil. Similar effects with smoother onset and longer duration per dose.

Dose range75–150mg
Half-life15h
Onset60min
Safety3/5high evidence base

Mechanism of action

Same as modafinil — dopamine reuptake inhibition, orexin modulation. The R-enantiomer has longer half-life.

Benefits

  • Smoother wakefulness vs modafinil

    EVIDENCEA

    Direct head-to-head comparisons.

Side effects

  • Headachecommonmoderate
  • Insomniauncommonmoderate

Where to buy

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