Back to Dihexa

Safety question

Is Dihexa safe?

High risk — avoid casual recreational use. Dihexa scores 1/5. Serious adverse events are documented in the clinical or coroner record. Use is appropriate only for narrowly-indicated medical purposes under specialist supervision.

Safety score

1 / 5

Evidence grade

C

Severe reactions on file

1

Pubmed cites

25

Key facts

typical dose
5–35 mg
dose frequency
1 dose
timing
AM
with food
optional
safety score
1/5
evidence grade
C
class
peptide
PubMed citations
25
legal status (US)
Research-chemical category
legal status (UK)
Research-chemical category
legal status (EU)
Research-chemical category
legal status (AU)
Research-chemical category
primary mechanism
Activates the hepatocyte growth factor (HGF) / Met receptor system in neurons, which promotes dendritic spine formation and synaptogenesis.

Common side effects

Severe reaction risks

Dihexa has the following documented severe adverse reactions: No human safety data. These are rare but require immediate medical attention if they occur.

Who should not take Dihexa

What "safe" means here

Our safety scoring reflects (a) published clinical and observational literature on healthy-adult use at standard supplement doses, (b) the spectrum of adverse-event reports in the medical and supplement-pharmacovigilance record, and (c) the regulatory status across major jurisdictions. It does notreflect long-term outcomes in populations that haven’t been studied, and it does not substitute for clinical judgement applied to your individual situation.

A 5/5 score does not mean “no risk” — it means risk has been quantified as low in healthy adults at usual doses. Idiosyncratic and allergic reactions are possible with virtually any compound, including those we rate highest.

Full mechanism, citations, and dose guidance for Dihexa are on the main reference page — see Dihexa. For the dose-by-dose breakdown, see Dihexa dosage. To check stack interactions, use the interaction checker.

This page is informational. It is not medical advice and does not establish a clinician-patient relationship. Individual risk varies with genetics, medications, pre-existing conditions, and dose. Always consult a qualified clinician before starting a new compound. See our full disclaimer and terms.