Comparison
Modafinil vs Caffeine
Modafinil
Eugeroic developed for narcolepsy; one of the most popular prescription cognitive enhancers. Sustained alertness without traditional stimulant side effects.
Caffeine
The world's most widely consumed psychoactive substance. Adenosine receptor antagonist enhancing alertness and attention.
| Field | Modafinil | Caffeine |
|---|---|---|
| Category | stimulant | stimulant |
| Dose range | 100–200mg | 50–400mg |
| Half-life | 14h | 5h |
| Onset | 45min | 30min |
| Evidence | EVIDENCEA | EVIDENCEA |
| Safety | ●●●○○ | ●●●●○ |
| Legal (US) | USSchedule IV | USOTC |
| PubMed refs | 3200 | 25000 |
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