Comparison
Modafinil vs Adrafinil
Modafinil
Eugeroic developed for narcolepsy; one of the most popular prescription cognitive enhancers. Sustained alertness without traditional stimulant side effects.
Adrafinil
Prodrug of modafinil. Converted in the liver. Used historically before modafinil was widely available.
| Field | Modafinil | Adrafinil |
|---|---|---|
| Category | stimulant | stimulant |
| Dose range | 100–200mg | 300–1200mg |
| Half-life | 14h | 1h |
| Onset | 45min | 60min |
| Evidence | EVIDENCEA | EVIDENCEB |
| Safety | ●●●○○ | ●●●○○ |
| Legal (US) | USSchedule IV | USUnscheduled |
| PubMed refs | 3200 | 60 |
Build a stack with bothOpen builder →
Check interactionsOpen checker →