Comparison
Magnesium L-Threonate vs Sulforaphane (Broccoli Sprout)
Magnesium L-Threonate
MIT-developed magnesium that crosses the blood-brain barrier. Shown to enhance synaptic density and reduce 'brain age'.
Sulforaphane (Broccoli Sprout)
Isothiocyanate from cruciferous vegetables. Activates Nrf2 antioxidant signaling. Studied for cancer prevention, autism, and metabolic health.
| Field | Magnesium L-Threonate | Sulforaphane (Broccoli Sprout) |
|---|---|---|
| Category | neuroprotective | neuroprotective |
| Dose range | 1000–2000mg | 10–40mg |
| Half-life | 6h | — |
| Onset | — | — |
| Evidence | EVIDENCEB | EVIDENCEB |
| Safety | ●●●●● | ●●●●● |
| Legal (US) | USOTC | USOTC |
| PubMed refs | 90 | 4200 |
The comparison in plain English
Auto-generated from dataMagnesium L-Threonate and Sulforaphane (Broccoli Sprout) are both in the neuroprotective category respectively. Magnesium L-Threonate MIT-developed magnesium that crosses the blood-brain barrier. Sulforaphane (Broccoli Sprout) Isothiocyanate from cruciferous vegetables.
Bottom line
Magnesium L-Threonate (evidence B, safety 5/5) matches the evidence base of Sulforaphane (Broccoli Sprout) (evidence B, safety 5/5). Magnesium L-Threonate has the slightly cleaner safety profile. For users new to either, the higher-evidence option is the safer first try.
Choose Magnesium L-Threonate if
Magnesium L-Threonate is the better fit when your goal aligns with its mechanism (L-threonate is a sugar-acid carrier that uniquely enables magnesium to cross the blood-brain barrier in meaningful quantities — most oral magnesium forms (oxide, citrate, glycinate) raise serum magnesium but not central magnesium) and the dose range (1000–2000mg) suits your protocol. Half-life is 6h.
Choose Sulforaphane (Broccoli Sprout) if
Sulforaphane (Broccoli Sprout) is the better fit when your goal aligns with its mechanism (Most potent natural activator of Nrf2 (nuclear factor erythroid 2-related factor 2), the master regulator of the cellular antioxidant response) and the dose range (10–40mg) suits your protocol. Half-life is —h.