Nicotinamide Mononucleotide Description
Nicotinamide Mononucleotide (NMN) is a derivative of Niacin, a form of vitamin B3 and is also known as nicotinic acid. The body can use NMN as a very efficient precursor to NAD+, which people need in order for their bodies and minds to run at peak performance. NAD+ is an essential coenzyme that plays important roles in various metabolic pathways and it has been confirmed that increasing its overall content can help with treating a wide variety of pathophysiological conditions. The higher your NAD+ levels, the more cellular energy you will have available, and the better your body and mind will be able to function in highly demanding situations.
Benefits of Nicotinamide Mononucleotide
NMN may have a plethora of benefits that can be summarized in five main categories:
1. NMN may help promote cardiovascular function
One of the most evident benefits of NMN is its effect on our cardiovascular system and blood flow in general. Within the cardiovascular system, NMN can quickly turn into NAD+, which is a very important molecule for cardiovascular support.
2. NMN may help promote energy levels
NMN is widely known for its ability to help promote energy levels in individuals of all ages. NMN achieves this via a few different mechanisms and its energy promoting effects appear to be one of the most consistent and noticeable effects. An NMN supplement will allow us to derive more energy from the food we eat, which can lead to higher levels of physical activity, and may even help promote weight loss.
The influence NMN has on metabolism seems to be especially important for healthy ageing. As we get older, we get less efficient at turning food into energy. This may lead to weight gain and overall low energy levels. Taking an NMN supplement would thus help you turn food more efficiently into energy.
3. NMN may help promote sleep quality
Our Circadian rhythms also heavily influence our moods, and it appears that the better our circadian rhythm functions, the better our overall mood may be.
4. NMN may help promote longevity
The longevity-promoting effects of NMN are rooted in its ability to promote cardiovascular function, energy metabolism and sleep quality. By replenishing our bodies with NAD+ through an NMN supplement, we can help support these vital processes that rely on adequate NAD+ levels. This should support overall longevity and promote a better quality of life as we age.
5. It may help promote a positive mood
Taking an NMN supplement could boost your mood. NMN would make a very solid foundation for a mood-boosting stack. In fact, it stacks very well with L-Theanine and Melatonin.
Where to Buy Nicotinamide Mononucleotide Online
At Nootropics.com, you can buy Nicotinamide Mononucleotide in a jar of 60x125mg capsules. All of our products are quality tested once after manufacturing, and then undergo a stringent process of quality assurance by an independent third-party lab. We test for identity, purity, and an array of heavy metals using FTIR and HPLC. Our products use vegetable capsules suitable for vegans.
Our customers get free shipping on orders over $70 in the US and $200 for international orders. If you buy 2 or more jars of NMN, we offer a 5% and 10% discount. We offer a money-back guarantee 90 days after you buy our products.
Nicotinamide Mononucleotide Guidelines
NMN dosage: 1-2 capsules per day
Effect onset: 10 – 15 minutes
Long-term effects: With the promising therapeutic properties that NMN showed in animal studies, researchers are aiming to understand how this molecule works in the human body. A recent clinical trial in Japan demonstrated that the molecule is safe and well-tolerated at the used dosage. More studies and human trials are on the way.
Storage note: It is important to store NMN in a cool and dry place. Keep away from direct sunlight and heat.
COVID-19 note: During the pandemic, NMN is receiving more and more attention for its role in maintaining the immune system balance, which may be a possible treatment for the coronavirus-caused cytokine storm. With the preliminary studies showing some positive results, many scientists and physicians believe the NAD+ booster’s effect on COVID-19 is worth investigating .
Coating: NMN as a powder is very unstable and needs to be stored at low temperatures. Everything that happens before NMN goes into a tablet may lead to significant degradation. This is why our NMN is stored at -20 degrees Celsius, right up until the point where it gets pressed into a tablet. This minimizes any degradation that can occur to NMN when it is in its fragile powder form. We take this one step further by adding an enteric coating to our capsules, a process which allows NMN to pass through our stomach safely without loss or degradation until it reaches the small intestine where it can thus be better absorbed.
Always consult with a qualified healthcare physician before taking any new dietary supplement. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Third-party purity testing:
Certificate of Authenticity – NMN
Chemical name: nicotinamide mononucleotide
Other names: beta-nicotinamide mononucleotide
Side effects: This molecule is largely considered to be safe and not toxic, even at high concentrations in mice and in a human study. Long-term (one-year) oral administration in mice does not have toxic effects. The very first clinical trial in humans was completed and the evidence supports the idea that it is not toxic in single doses . If you experience unintended side effects, please exercise caution. If discomfort persists or intensifies, always consult a medical practitioner.
Further information (off-site)
What is NMN?
1. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice
2. Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition
3. About NMN (Beta-Nicotinamide Mononucleotide)
4. Slc12a8 is a nicotinamide mononucleotide transporter
5. Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men
6. Effect of long-term oral administration of nicotinamide mononucleotide (NMN) on human health
7. Assessment of the safety of long-term nicotinamide mononucleotide (NMN)
8. The emergence of the nicotinamide riboside kinases in the regulation of NAD+ metabolism
9. Nicotinamide Mononucleotide: Exploration of Diverse Therapeutic Applications of a Potential Molecule
10. Nicotinamide mononucleotide (NMN) supplementation ameliorates the impact of maternal obesity in mice: comparison with exercise
11. What is Nicotinamide Mononucleotide (NMN)?