Pramiracetam: Everything You Need to Know

Do you want to learn more about Pramiracetam? Maybe you’re trying to research it, but the information is scarce? If that’s the case, then you should read this comprehensive guide.

In this guide, you’ll learn about dosage, reviews, side effects, benefits, and the comparison of Pramiracetam vs. Phenylpiracetam.

Pramiracetam is a nootropic marketed as a treatment for attention deficits and memory loss for older adults who have neurodegenerative dementia. As of today, it is marketed in Italy by a pharmaceutical company named Menarini.


According to this Wikipedia article, Pramiracetam has been around for a long time and was originally discovered in the 1970s by Parke-Davis scientists. Parke-Davis was a division of Warner-Lambert, an American pharmaceutical company. It was originally developed to treat Alzheimer’s Disease. Unfortunately, clinical trials stopped due to mixed results.

Pramiracetam is used and sold today in Italy under the brand of Pramistar. Pramistar is said to treat users who experience memory loss and attention deficits.

Users consider taking Pramiracetam if they are seeking to improve mental acuity, to fight memory loss, and some users have also sought the chemical to help relieve anxiety and to improve confidence in social situations.

After analyzing the reviews of users who have experimented with Pramiracetam, it’s clear that this is one of the strongest chemicals in the racetam family of drugs. Later in this guide, we’ll dive deeper into the many reviews that users have left from around the web so you can get a better indicator of how Pramiracetam works and how others perceive the nootropic.

Quick facts about Pramiracetam:

  • A nootropic and CNS (central nervous system) stimulant.
  • Originally discovered by Parke-Davis, an American pharmaceutical company.
  • Currently marketed by Menarini, an Italian pharmaceutical company.
  • Available under the brand name of Pramistar.
  • Marketed as a treatment for older people experiencing attention deficits and memory loss.
  • Also known as CI-879.
  • The chemical formula of C₁₄H₂₇N₃O₂ (Source).

Pramiracetam dosage

The first thing to do when considering the perfect Pramiracetam dosage is to ask your favorite medical or healthcare provider for their council regarding which dosage is right for you. Also, be sure to pay very close attention to the instructions that the manufacturer or nootropic agent provides to you.

Another hugely important thing to remember is that your unique body, your health, your metabolism, and any medications you are taking may impact how different nootropics and medications interact with your unique body chemistry. For that reason, it’s essential for you to contact your doctor or preferred medical council before experimenting with Pramiracetam or any nootropic or medication.

There aren’t many clinical trials involved in humans that are readily available and published to read online. However, there is this one Pramiracetam study that reveals improved memory in patients who suffered a head injury. During the study, 400 mg of Pramiracetam was administered three times per day. The study can perhaps serve as some indication or starting point for you and your doctor to discuss.

If you’re new to trying Pramiracetam, then it’s critically important for you to start at a very small dosage. That’s because Pramiracetam is widely considered to be one of the most potent chemicals in the racetam family of drugs, and there is an abundance of anecdotal evidence in the form of reviews from users signifying that it is indeed very powerful!

As always, it’s best to experiment, starting at a very small dosage after consulting with your primary healthcare provider. Also, be sure to pay close attention to any instructions provided by the drug manufacturer.

Based on  this study published on PubMed and our studying of Pramiracetam user reviews, the common dosage is 400 mg 3 times per day.

Other users on social media indicate a smaller dosage of 200 mg, or even smaller.

Pramiracetam reviews

As you begin to read different Pramiracetam reviews from around the web, you might be shocked to find many rave reviews from users who love how the nootropic makes them feel. On several occasions, end users swear by the way it makes them socially confident, mentally quick, and capable of engaging socially with utter confidence.

This thorough Pramiracetam review found on Reddit showcases one such rave review where the user describes how it made them feel sharp, witty, and socially affable. Of course, such reviews are anecdotal. However, if you spend time researching Pramiracetam, you’ll probably agree that many reviewers are attesting to the chemical’s ability to improve mental clarity and function.

Of course, your results may vary, and it’s always advised to consult your doctor before you consider experimenting with any nootropic or medication.

Other reviews indicate how powerful Pramiracetam is, so if you intend on experimenting with it, be sure to start at a very small dosage! One reviewer even indicated how they swear that Pramiracetam aided them in passing a test. If you want to read more reviews on social media, here’s a Reddit link that will showcase a few reviews on Reddit.

Pramiracetam side effects

As you experiment with any nootropic, it’s always crucial to pay very close attention to how your unique body and brain respond! It’s true that you may experience better attention to detail or even more mental energy, but also be wary of how your body responds because everyone is unique, and there are surprisingly few clinical trials that reveal side effects of Pramiracetam.

According to this study, there were no significant side effects for volunteers taking Pramiracetam at any dosage level. Another study published here cites that Pramiracetam boasts a “wide margin” of safety when tested on animals and human volunteers.

In addition to human trials, there’s also an abundance of reviews on social media to help gather a rudimentary understanding of side effects.

One of the biggest and most undesirable of Pramiracetam side effects that you’ll discover after reading reviews on different storefronts and social media website is that many users describe the taste as terrible! If you do indeed try to experiment with Pramiracetam, and especially if you are easily turned off by weird tastes, consider masking the flavor or asking your nootropic manufacturer for a capsule form.

Pramiracetam may affect your body in the following ways:

  • Terrible taste.
  • Mood.
  • Anxiety levels.
  • Energy levels.

Pramiracetam benefits

In current day Italy Pramiracetam is marketed as a treatment for memory and attention deficits. The ability to achieve memory gains is easily one of the most powerful benefits of Pramiracetam. A study found on PubMed reveals that memory gains from a test group administered Pramiracetam outperformed those not administered the drug.

Another very important Pramiracetam trial (which you can read here) involved evaluating cognitive problems in males who have sustained a brain injury. The results of the study show that the ability to recall improved after the administration of pramiracetam.

Another study (found here) reveals how Pramiracetam can help prevent symptoms of amnesia. During the study, patients were divided into groups and issued two different treatment options.

One group was issued Pramiracetam, and the other group was issued Piracetam. The study shows that both groups had positive results. Patients experiencing head injuries noted “considerable improvement” and disappearance of headaches, nausea, and dizziness. Pramiracetam was found to be better if the patients suffer amnesia.

Overall, there have been a handful of clinical trials that seem to indicate that Pramiracetam can indeed offer some improved brain function in humans under certain situations.

Another very vibrant and rich source of Pramiracetam knowledge is social media. Users on Reddit have said how Pramiracetam helps to improve mental clarity, can reduce anxiety, and helps focus and generally to improve mental quickness. Of course, any comment on social media is arbitrary, however, may prove helpful and at the very least, fascinating.

Pramiracetam vs Phenylpiracetam

If you’re thinking about trying Pramiracetam to improve your mental faculties, then there’s a good chance that you’ve also heard of Phenylpiracetam. Phenylpiracetam is said to be a tremendously powerful nootropic that grants cognitive as well as physical enhancements.

According to Wikipedia, Phenylpiracetam is usually prescribed as a stimulant to help alleviate high levels of stress. Fascinatingly enough, Phenylpiracetam can also help to increase tolerance to extreme temperatures.

Another interesting piece of information is that The World Anti-Doping Agency has listed “4-Phenylpiracetam” as a prohibited stimulant. You can read the prohibited list in their 2017 issue published in this PDF found on the organization’s website.

You might be interested to know that according to Google trends, Phenylpiracetam is significantly more popular than Pramiracetam.


Have you ever been speaking to someone, and you can’t exactly remember what word you’re trying to use? Or maybe your mind goes blank whenever someone asks you a question?

This type of frustration is what those suffering from amnesia and dementia can feel every single day of their lives.

The truth is that memory loss is a serious problem. Dementia and amnesia are both frightening ailments that plague people from every corner of the planet.

Drugs such as Pramiracetam might not be the magic bullet that can suddenly cure amnesia. However, the clinical trials that test Pramiracetam and involve cognitive function are very promising for those who suffer from memory loss, amnesia, or certain types of dementia.

Remember that experimenting with Pramiracetam or any other nootropic is serious. Your unique brain chemistry and body may interact with the chemical in ways that you haven’t anticipated. That’s why it’s so important to consult with your preferred healthcare professional to discuss if Pramiracetam might be an option for treating your memory loss or symptoms of cognitive dysfunction.

Finally, remember that while the clinical trials that test Pramiracetam are impressive, overall, there haven’t been many trials involving humans. For that reason, it’s always direly critical to consult with your doctor before using Pramiracetam.