Lion’s Mane Benefits: a Guide to This Unique Mushroom

Lion's mane mushrooms

What can Lion’s Mane do for you? An overview

Lion's Mane Mushroom nootropic capsules 500mg

Lion’s Mane mushroom is an ancient Chinese remedy traditionally used for improving cognitive performance, and overall health. It may prevent and treat nerve damage by boosting Brain Nerve Growth Factor, and neurogenesis – the process by which new neurons are formed in the brain.

Lion’s Mane may help improve focus and attention, boost thinking, repair brain cells, help depression and anxiety, and manage other neurological problems like Alzheimer’s, dementia, Parkinson’s, and muscular dystrophy. [1]

Lion’s Mane may help in these ways:

  • Potentially stimulates Nerve Growth Factor (NGF) in the brain.
  • May prevent and treat nerve damage in the brain. Once past the blood-brain barrier, Lion’s Mane stimulates enzyme production that releases Nerve Growth Factor (NGF). Nerve regeneration helps relieve neurodegenerative disease symptoms such as Alzheimer’s, dementia, and Parkinson’s Disease.
  • Neurogenesis. Lion’s Mane stimulates the repair and creation of neurons. Boosting neurotransmitters and signaling that affects memory, learning, recall, and mood.
  • Brain optimization. Lion’s Mane may help eliminate brain fog, restoring memory and mental alertness. It may improve anxiety and depression symptoms.

Here are some extra readings about the benefits of Lion’s Mane:

Digging Deeper on Lion’s Mane

Lion’s Mane (Hericium Erinaceus) is an ancient Chinese medicinal mushroom with powerful properties proven to improve brain health, enhance cognition, and protect the brain against injury, disease, and the effects of ageing. It is quickly becoming universally recognized as a supplement that provides a wide array of benefits. [2] It grows naturally in the wild in Europe, Asia, and North America – beginning to grow in the late summer through the fall, primarily on hardwood trees.

Lion's Manu mushroom - 5 images

It is certainly a unique and exceptionally promising natural nootropic that belongs to the edible tooth fungi group. It is sometimes referred to as ‘bearded tooth mushroom’, ‘hedgehog mushroom’, and even ‘pom pom mushroom’ because of its long dangling clusters of spines.

These mushrooms are also prized for their nutritional and culinary qualities . They are typically dried and ground into a powder to make Lion’s Mane mushroom capsules. The extract for the capsules is made from the whole mushroom that you can see above the ground by breaking down the cell walls of the mushroom with hot water in order to get to the beta-d-glucans trapped within the cell walls. Lion’s Mane Mushroom has been recognized as potentially stimulating Nerve Growth Factor (NGF) in the brain.

Known for its powerful effects as a “brain tonic”, Lion’s Mane is said to have been used as a tea for thousands of years by Buddhist monks to enhance brain power, and heighten their ability to focus during meditation.

Lion’s Mane may be a powerful catalyst for brain cell regeneration helping improve memory and cognition.

The primary active compounds in Lion’s Mane are hericenones and erinacines. Hericenones help your brain produce more Nerve Growth Factor (*). And erinacines easily cross the blood-brain barrier to boost the production of neurons (*).

How does Lion’s Mane feel when you take it?

You may not experience the effects of supplementing with Lion’s Mane Mushroom immediately. But with continued use of Lion’s Mane, many users report a boost in mood and mental energy.

Some report it increases depth perception and an improvement in sense of smell. Others testify to improved decision-making, the ability to solve problems and learning. These statements suggest Lion’s Mane has the ability to improve neuroplasticity. [1]

The overall consensus is that Lion’s Mane has the ability to lessen anxiety, reduce depression, and improve concentration. [1]

Recent research on Lion’s Mane mushroom

Lion’s Mane prevents cognitive dysfunction

In this study, researchers examined the effects of Lion’s Mane on amyloid β(25-35) peptide-induced learning and memory deficits in mice. Amyloid β(25-35) peptide is implicated in diseases like Alzheimer’s.

Mice were injected with the peptide on days 7 and 14 of the trial. And they were fed a diet containing Lion’s Mane over 23-days of the experiment. The results showed that Lion’s Mane prevented short-term and visual recognition memory reduction normally induced by amyloid β(25-35) peptide.

They concluded that Lion’s Mane Mushroom “may be useful in the prevention of cognitive dysfunction”. [1]

Lion’s Mane induces Nerve Growth Factor

In this trial, mice were fed Lion’s Mane 5% freeze-dried powdered extract for 7 days. Researchers found an increase in the level of Nerve Growth Factor (NGF) in the brain of the mice. Concluding that Lion’s Mane “contains active compounds that stimulate NGF synthesis”. [1]

Lion’s Mane Repairs Nerves

In this study done with rats, Lion’s Mane extract was able to promote neuron regrowth after injury. Rats with damaged nerve cells were able to walk again after consuming water containing Lion’s Mane extract.

The researchers concluded that Lion’s Mane regenerates damaged nerve cells. In this case, the reversal was so profound, the rats went from being totally disabled to walking again. [1]

Lion’s Mane side effects

Lion’s Mane Mushroom is non-toxic and considered very safe with few side effects reported.

Some people report itchy skin from higher doses. Likely attributable to a boost in Nerve Growth Factor.

Lion’s Mane has been tested in animals showing no side effects or toxicity even up to 5 grams per kilogram. [1]


If you take Lion’s Mane mushroom as a dietary supplement, we recommend you to take 1 – 2 capsules per day.

Where to Buy Lion’s Mane mushroom

At, you can buy Lion’s Mane mushroom in a jar of 60x500mg capsules.

All of our products are quality tested once after manufacturing, and then undergo a stringent process of quality assurance by an independent third-party lab. You can find a link to our Certificate of Authenticity on the Lion’s Mane product page. We test for identity, purity, and use FTIR and HPLC to make sure the sample does not contain heavy metals.

Our customers get free shipping on orders over $70 in the US and $200 for international orders. If you buy 2 or more jars, you get a 5% and 10% discount. We offer a money-back guarantee 90 days after you buy any of our products.

We only use vegetable capsules suitable for vegans.


[1]  Tomen, David (2020). Secrets of the Optimized Brain: 92 Nootropics to Unlock your True Brain Potential. Nootropics Expert (3rd Edition). [available at:]

[2] Neuronal Health – Can Culinary and Medicinal Mushrooms Help?

[3] Neurological Activity of Lion’s Mane (Hericium Erinaceus)

[4] Reduction…by 4 Weeks Hericium Erinaceus Intake

[5] Improving Effects of the Mushroom Yamabushitake (Hericium Erinaceus) on Mild Cognitive Impairment: a Double-Blind Placebo-Controlled Clinical Trial

[6] Nerve Growth Factor-Inducing Activity of Hericium Erinaceus in 1321N1 Human Astrocytoma Cells

[7] Antihyperglycemic and Antihyperlipidemic Activities of Aqueous Extract of Hericium Erinaceus in Experimental Diabetic Rats

[8] Anti-Fatigue Activities of Polysaccharides Extracted from Hericium Erinaceus

[9] Hericium Erinaceus

Further information 

  1. Article
  2. Wikipedia
  3. Healthline
  4. Braintropic